Phenylephrine hydrochloride

Phenylephrine hydrochloride

Synonyms: (-)-alpha-hydroxy-beta-(methylamino)ethyl-alpha-(3-hydroxybenzene)hydrochlor;1-m-hydroxy-alpha-(methylaminomethyl)benzylalcoholhydrochloride;3-hydroxy-alpha-((methylamino)methyl)-,hydrochloride,(-)-benzenemethano;almefrin;benzenemethanol,3-hydroxy-alpha-[(methylamino)methyl]-,hydrochloride,(thet;consdrin;consdrinhydrochloride;d-(-)-phenylephrinehydrochloride
CAS: 61-76-7
MF: C9H14ClNO2
MW: 203.67
EINECS: 200-517-3

Chemical Properties white to almost white crystalline powder
Usage α-Adrenergic agonist. Mydriatic; decongestant.
General Description Odorless white microcrystalline powder. Bitter taste. pH (1% aqueous solution) about 5.
Air & Water Reactions May be sensitive to prolonged exposure to air and light. Water soluble.
Reactivity Profile Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts.
Fire Hazard Flash point data for Phenylephrine hydrochloride are not available; however, Phenylephrine hydrochloride is probably combustible.
Biological Activity α 1 -adrenoceptor agonist; pK i values are 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively.